:root{--bg-primary:#070a10;--bg-secondary:#0b101b;--bg-card:#0d131fdb;--bg-card-hover:#11192af0;--border-color:#94a3b81f;--border-hover:#38bdf859;--primary:#0ea5e9;--primary-hover:#38bdf8;--primary-glow:#0ea5e924;--secondary:#6366f1;--secondary-glow:#6366f124;--text-main:#f8fafc;--text-muted:#94a3b8;--text-dim:#64748b;--color-success:#10b981;--color-success-bg:#10b98114;--color-warning:#f59e0b;--color-warning-bg:#f59e0b14;--color-danger:#ef4444;--color-danger-bg:#ef44441a;--color-info:#06b6d4;--color-info-bg:#06b6d414;--shadow-sm:0 1px 2px #00000059, inset 0 1px 0 #ffffff0a;--shadow-md:0 12px 32px -12px #000000bf, 0 1px 2px #0006, inset 0 1px 0 #ffffff12;--shadow-hover:0 18px 38px -12px #000000d9, 0 0 24px #0ea5e912, inset 0 1px 0 #ffffff1f;--shadow-glow:0 0 20px #0ea5e92e;--glass-blur:blur(18px);--font-heading:"Plus Jakarta Sans", "Outfit", -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;--font-body:"Plus Jakarta Sans", "Inter", -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif;--font-serif:"Newsreader", Georgia, Cambria, "Times New Roman", serif;--font-mono:"JetBrains Mono", "Fira Code", ui-monospace, SFMono-Regular, monospace;--transition-fast:.16s cubic-bezier(.16, 1, .3, 1);--transition-normal:.28s cubic-bezier(.16, 1, .3, 1);--sidebar-bg:#090d16f0;--tab-navigation-bg:#090e18eb;--tab-btn-hover-bg:#ffffff0a;--timeline-content-bg:#0f1624bf;--timeline-content-border:#94a3b81f;--table-th-bg:#0b111df5;--table-td-border:#94a3b814;--upload-zone-bg:#0b111da6;--onboarding-banner-bg:#0b111dbf;--mock-dashboard-bg:#090e18e6;--mock-header-bg:#0c1320f5;--input-bg:#090e18e6;--footer-bg:#ffffff05;--step-num-bg:#ffffff0a;--toolbar-bg:#0b111de0;--btn-clinical-bg:#111928d9;--btn-clinical-hover:#182338f2;--bg-gradient:radial-gradient(circle at 12% 0%, #0ea5e90e 0%, transparent 48%), radial-gradient(circle at 88% 100%, #6366f10b 0%, transparent 48%);--title-gradient:linear-gradient(135deg, #fff 55%, #e0f2fe 100%)}:root[data-theme=light]{--bg-primary:#f4f6f9;--bg-secondary:#ebeef4;--bg-card:#fffffff5;--bg-card-hover:#fff;--border-color:#0f172a1a;--border-hover:#0284c759;--primary:#0369a1;--primary-hover:#0284c7;--primary-glow:#0369a11a;--secondary:#4338ca;--secondary-glow:#4338ca14;--text-main:#0f172a;--text-muted:#334155;--text-dim:#64748b;--color-success:#047857;--color-success-bg:#04785714;--color-warning:#b45309;--color-warning-bg:#b4530914;--color-danger:#b91c1c;--color-danger-bg:#b91c1c14;--color-info:#0e7490;--color-info-bg:#0e749014;--shadow-sm:0 1px 2px #0f172a0d;--shadow-md:0 8px 24px -6px #0f172a12, 0 1px 2px #0f172a0a, inset 0 1px 0 #fff;--shadow-hover:0 14px 30px -8px #0f172a1c, inset 0 1px 0 #fff;--shadow-glow:0 0 16px var(--primary-glow);--sidebar-bg:#fff;--tab-navigation-bg:#eef2f6;--tab-btn-hover-bg:#0f172a0a;--timeline-content-bg:#f8fafc;--timeline-content-border:#0f172a17;--table-th-bg:#f1f5f9;--table-td-border:#0f172a12;--upload-zone-bg:#f8fafc;--onboarding-banner-bg:#fff;--mock-dashboard-bg:#fff;--mock-header-bg:#f8fafc;--input-bg:#fff;--footer-bg:#0f172a08;--step-num-bg:#0f172a0d;--toolbar-bg:#fffffff2;--btn-clinical-bg:#f8fafc;--btn-clinical-hover:#f1f5f9;--bg-gradient:radial-gradient(circle at 12% 0%, #0369a109 0%, transparent 48%), radial-gradient(circle at 88% 100%, #4338ca06 0%, transparent 48%);--title-gradient:linear-gradient(135deg, #0f172a 60%, #0369a1 100%)}*{box-sizing:border-box;scrollbar-width:thin;scrollbar-color:#38bdf840 transparent;margin:0;padding:0}html,body{width:100%;max-width:100%;overflow-x:hidden}body{background-color:var(--bg-primary);background-image:var(--bg-gradient);color:var(--text-main);font-family:var(--font-body);-webkit-font-smoothing:antialiased;-moz-osx-font-smoothing:grayscale;min-height:100vh}h1,h2,h3,h4,h5,h6{font-family:var(--font-heading);letter-spacing:-.022em;font-weight:700}::-webkit-scrollbar{width:6px;height:6px}::-webkit-scrollbar-track{background:0 0}::-webkit-scrollbar-thumb{background:#94a3b840;border-radius:4px}::-webkit-scrollbar-thumb:hover{background:#38bdf873}.glass-card{background:var(--bg-card);-webkit-backdrop-filter:var(--glass-blur);border:1px solid var(--border-color);box-shadow:var(--shadow-md);transition:border-color var(--transition-fast), box-shadow var(--transition-fast), transform var(--transition-fast);border-radius:12px;padding:24px;position:relative}.glass-card:before{content:"";pointer-events:none;background:linear-gradient(90deg,#0000,#ffffff1f,#0000);height:1px;position:absolute;top:0;left:16px;right:16px}:root[data-theme=light] .glass-card:before{background:linear-gradient(90deg,#0000,#0369a11f,#0000)}.glass-card:hover{border-color:var(--border-hover);box-shadow:var(--shadow-hover)}.section-eyebrow{font-family:var(--font-mono);text-transform:uppercase;letter-spacing:.09em;color:var(--primary);align-items:center;gap:6px;font-size:.68rem;font-weight:600;display:inline-flex}.section-eyebrow:before{content:"";opacity:.85;background:currentColor;border-radius:1.5px;width:6px;height:6px;display:inline-block}.editorial-serif{font-family:var(--font-serif)}.mono-metric{font-family:var(--font-mono);font-variant-numeric:tabular-nums;letter-spacing:-.02em}.app-container{width:100vw;min-height:100vh;display:flex;overflow:hidden}.sidebar{background:var(--sidebar-bg);width:316px;min-width:316px;-webkit-backdrop-filter:var(--glass-blur);border-right:1px solid var(--border-color);z-index:10;flex-direction:column;gap:22px;padding:22px 20px;display:flex;overflow-y:auto}.main-content{flex-direction:column;flex-grow:1;gap:22px;height:100vh;padding:28px 36px;display:flex;overflow-y:auto}.dashboard-header{background:var(--bg-card);border:1px solid var(--border-color);border-left:3px solid var(--primary);box-shadow:var(--shadow-md);border-radius:12px;flex-direction:column;flex-shrink:0;gap:16px;margin-bottom:4px;padding:22px 26px;display:flex;position:relative}.article-title-badge{font-family:var(--font-mono);text-transform:uppercase;letter-spacing:.08em;color:var(--primary);background:var(--primary-glow);border:1px solid #0ea5e947;border-radius:6px;align-self:flex-start;padding:4px 10px;font-size:.72rem;font-weight:700}.article-main-title{font-family:var(--font-serif);letter-spacing:-.015em;color:var(--text-main);font-size:1.95rem;font-weight:600;line-height:1.24}.article-meta-row{color:var(--text-muted);flex-wrap:wrap;align-items:center;gap:14px;font-size:.88rem;display:flex}.meta-item{font-variant-numeric:tabular-nums;align-items:center;gap:6px;display:flex}.executive-toolbar{border-top:1px solid var(--border-color);flex-wrap:wrap;justify-content:space-between;align-items:center;gap:8px;width:100%;margin-top:2px;padding-top:14px;display:flex}.executive-toolbar-group{flex-wrap:wrap;align-items:center;gap:8px;display:flex}.btn-clinical{background:var(--btn-clinical-bg);color:var(--text-main);border:1px solid var(--border-color);font-family:var(--font-heading);letter-spacing:-.01em;cursor:pointer;transition:all var(--transition-fast);box-shadow:var(--shadow-sm);white-space:nowrap;border-radius:8px;align-items:center;gap:7px;padding:8px 13px;font-size:.81rem;font-weight:600;display:inline-flex}.btn-clinical:hover:not(:disabled){background:var(--btn-clinical-hover);border-color:var(--border-hover);transform:translateY(-1px);box-shadow:0 4px 12px #00000040}.btn-clinical:disabled{opacity:.6;cursor:not-allowed}.btn-clinical-primary{color:#fff;background:linear-gradient(#0ea5e9 0%,#0284c7 100%);border:1px solid #38bdf866;box-shadow:0 2px 10px #0ea5e940,inset 0 1px #fff3}.btn-clinical-primary:hover:not(:disabled){background:linear-gradient(#38bdf8 0%,#0ea5e9 100%);border-color:#7dd3fc99;box-shadow:0 4px 14px #0ea5e961,inset 0 1px #ffffff40}.tab-navigation-wrapper{-webkit-overflow-scrolling:touch;z-index:1;flex-shrink:0;width:100%;min-width:0;max-width:100%;margin-bottom:4px;display:block;position:relative;overflow-x:auto}.tab-navigation{background:var(--tab-navigation-bg);border:1px solid var(--border-color);box-shadow:var(--shadow-sm);border-radius:10px;flex-wrap:nowrap;gap:4px;width:fit-content;padding:5px;display:flex}.tab-btn{color:var(--text-muted);font-family:var(--font-heading);letter-spacing:-.01em;cursor:pointer;transition:all var(--transition-fast);background:0 0;border:1px solid #0000;border-radius:7px;flex-shrink:0;align-items:center;gap:7px;padding:8px 15px;font-size:.84rem;font-weight:600;display:flex;position:relative}.tab-btn:hover{color:var(--text-main);background:var(--tab-btn-hover-bg)}.tab-btn.active{color:#fff;background:linear-gradient(#0ea5e9 0%,#0284c7 100%);border-color:#38bdf859;font-weight:600;box-shadow:0 2px 8px #0ea5e947,inset 0 1px #fff3}.tabular-nums,.stat-value,.p-value-chip{font-family:var(--font-mono);font-variant-numeric:tabular-nums;font-feature-settings:"tnum"}.clinical-chip{border:1px solid var(--border-color);font-variant-numeric:tabular-nums;background:#ffffff06;border-radius:6px;align-items:center;gap:6px;padding:4px 10px;font-size:.78rem;font-weight:600;display:inline-flex}:root[data-theme=light] .clinical-chip{background:#f8fafc}.timeline{margin-top:16px;padding-left:28px;position:relative}.timeline:before{content:"";background:linear-gradient(to bottom, var(--primary), var(--secondary));width:2px;position:absolute;top:8px;bottom:8px;left:8px}.timeline-item{margin-bottom:28px;position:relative}.timeline-item:last-child{margin-bottom:0}.timeline-badge{background:var(--bg-primary);border:3px solid var(--primary);z-index:1;border-radius:50%;width:18px;height:18px;position:absolute;top:4px;left:-28px}.timeline-item:nth-child(2n) .timeline-badge{border-color:var(--secondary)}.timeline-content{background:var(--timeline-content-bg);border:1px solid var(--timeline-content-border);border-radius:12px;padding:16px 20px}.timeline-title{color:var(--text-main);margin-bottom:6px;font-size:1.1rem}@keyframes fadeInUp{0%{opacity:0;transform:translateY(12px)}to{opacity:1;transform:translateY(0)}}.fade-in-up{animation:fadeInUp var(--transition-normal) forwards}.grid-2{grid-template-columns:repeat(auto-fit,minmax(400px,1fr));gap:24px;display:grid}.grid-3{grid-template-columns:repeat(auto-fit,minmax(300px,1fr));gap:24px;display:grid}.table-wrapper{border:1px solid var(--border-color);border-radius:12px;margin-top:16px;overflow-x:auto}.custom-table{border-collapse:collapse;text-align:left;width:100%;font-size:.95rem}.custom-table th{background:var(--table-th-bg);color:var(--text-main);font-family:var(--font-heading);border-bottom:2px solid var(--border-color);padding:14px 18px;font-weight:600}.custom-table td{border-bottom:1px solid var(--table-td-border);color:var(--text-muted);padding:12px 18px}.custom-table tr:hover td{color:var(--text-main);background:#38bdf808}.btn-primary{background:var(--primary);color:#fff;font-family:var(--font-heading);cursor:pointer;transition:all var(--transition-fast);border:none;border-radius:8px;justify-content:center;align-items:center;gap:8px;padding:12px 20px;font-weight:600;display:flex;box-shadow:0 4px 12px #0ea5e933}.btn-primary:hover{background:var(--primary-hover);transform:translateY(-1px);box-shadow:0 6px 16px #0ea5e959}.upload-zone{text-align:center;cursor:pointer;transition:all var(--transition-fast);background:var(--upload-zone-bg);background-image:linear-gradient(90deg,#ffffff05 1px,#0000 1px),linear-gradient(#ffffff05 1px,#0000 1px);background-size:16px 16px;border:1.5px dashed #38bdf84d;border-radius:14px;flex-direction:column;align-items:center;gap:12px;padding:24px;display:flex;position:relative;overflow:hidden}.upload-zone:hover{border-color:var(--primary);background-color:#0ea5e90a;transform:translateY(-1px);box-shadow:0 0 25px #0ea5e91a,inset 0 1px #ffffff0d}.upload-zone.dragging{border-color:var(--color-success);background-color:#10b9810f;transform:scale(1.01);box-shadow:0 0 30px #10b98133}.clinical-tag{letter-spacing:.03em;border:1px solid var(--border-color);color:var(--text-muted);background:#ffffff0a;border-radius:4px;align-items:center;gap:4px;padding:2px 8px;font-size:.72rem;font-weight:600;display:inline-flex}.badge{text-transform:uppercase;border-radius:6px;padding:4px 8px;font-size:.75rem;font-weight:600}.badge-success{background:var(--color-success-bg);color:var(--color-success);border:1px solid #10b9814d}.badge-warning{background:var(--color-warning-bg);color:var(--color-warning);border:1px solid #f59e0b4d}.badge-danger{background:var(--color-danger-bg);color:var(--color-danger);border:1px solid #ef44444d}@media (width<=1024px){.app-container{flex-direction:column;width:100vw;max-width:100vw;height:auto;overflow:hidden auto}.sidebar{border-right:none;border-bottom:1px solid var(--border-color);width:100%;height:auto;max-height:400px}.main-content{box-sizing:border-box;width:100%;min-width:0;max-width:100%;height:auto;padding:20px 16px;overflow:hidden 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var(--border-color);color:var(--text-main);box-shadow:var(--shadow-sm);transition:all var(--transition-fast);border-radius:8px;align-items:center;gap:8px;padding:7px 14px;font-size:.8rem;font-weight:600;display:inline-flex}.hero-feature-pill:hover{border-color:var(--border-hover);transform:translateY(-1px)}.demo-card-enhanced{border:1px solid var(--border-color);cursor:pointer;transition:all var(--transition-fast);background:#ffffff05;border-radius:10px;flex-direction:column;gap:8px;padding:14px 16px;display:flex;position:relative;overflow:hidden}:root[data-theme=light] .demo-card-enhanced{background:#f8fafc}.demo-card-enhanced:before{content:"";background:var(--primary);opacity:.35;width:3px;height:100%;transition:opacity var(--transition-fast);position:absolute;top:0;left:0}.demo-card-enhanced:hover{border-color:var(--border-hover);box-shadow:var(--shadow-md);background:#ffffff09;transform:translateY(-1px)}:root[data-theme=light] .demo-card-enhanced:hover{background:#fff}.demo-card-enhanced:hover:before{opacity:1}.demo-stat-pill{font-family:var(--font-mono);font-variant-numeric:tabular-nums;background:var(--primary-glow);color:var(--primary);border:1px solid #0ea5e938;border-radius:4px;padding:2px 7px;font-size:.7rem;font-weight:600}.welcome-grid{grid-template-columns:1.1fr 1fr 1.3fr;gap:24px;width:100%;display:grid}@media (width<=1400px){.welcome-grid{grid-template-columns:1fr 1fr}.welcome-grid-mockup-col{grid-column:span 2}}@media (width<=768px){.welcome-grid{grid-template-columns:1fr}.welcome-grid-mockup-col{grid-column:span 1}.grid-2,.grid-3{grid-template-columns:1fr;gap:16px}}.onboarding-banner{background:var(--onboarding-banner-bg);border:1px solid var(--border-color);width:100%;box-shadow:var(--shadow-sm);border-radius:12px;flex-wrap:wrap;justify-content:space-between;align-items:center;gap:16px;padding:16px 24px;display:flex}.onboarding-steps{flex-wrap:wrap;align-items:center;gap:12px;display:flex}.onboarding-step{align-items:center;gap:8px;display:flex}.step-num{background:var(--step-num-bg);border:1px solid var(--border-color);width:24px;height:24px;color:var(--text-muted);font-family:var(--font-mono);transition:all var(--transition-fast);border-radius:6px;justify-content:center;align-items:center;font-size:.74rem;font-weight:700;display:flex}.onboarding-step.active .step-num{background:var(--primary);color:#fff;border-color:var(--primary);box-shadow:0 0 10px var(--primary-glow)}.onboarding-step.completed .step-num{background:var(--color-success-bg);color:var(--color-success);border-color:var(--color-success)}.step-text{color:var(--text-muted);font-size:.82rem;font-weight:600}.onboarding-step.active .step-text{color:var(--text-main)}.step-arrow{color:var(--text-dim);font-size:.85rem}.mock-dashboard-card{background:var(--mock-dashboard-bg);border:1px solid var(--border-color);box-shadow:var(--shadow-md);height:100%;min-height:440px;transition:border-color var(--transition-normal);border-radius:12px;flex-direction:column;display:flex;overflow:hidden}.mock-dashboard-card:hover{border-color:var(--border-hover)}.mock-header{background:var(--mock-header-bg);border-bottom:1px solid var(--border-color);flex-direction:column;gap:6px;padding:16px 20px;display:flex}.mock-body{background-image:linear-gradient(90deg,#94a3b808 1px,#0000 1px),linear-gradient(#94a3b808 1px,#0000 1px);background-size:20px 20px;flex-direction:column;flex-grow:1;gap:16px;padding:20px;display:flex}.mock-tabs{border:1px solid var(--border-color);background:#00000040;border-radius:8px;gap:6px;padding:4px;display:flex}:root[data-theme=light] .mock-tabs{background:#eef2f6}.mock-tab{color:var(--text-dim);font-family:var(--font-heading);cursor:pointer;transition:all var(--transition-fast);text-align:center;background:0 0;border:none;border-radius:6px;flex:1;padding:6px 10px;font-size:.78rem;font-weight:600}.mock-tab:hover{color:var(--text-muted)}.mock-tab.active{background:var(--primary-glow);color:var(--primary);border:1px solid #0ea5e94d}.specialty-badge{font-family:var(--font-mono);text-transform:uppercase;letter-spacing:.06em;border-radius:4px;align-items:center;padding:2px 8px;font-size:.64rem;font-weight:700;display:inline-flex}.specialty-cardio{color:var(--primary);background:#0ea5e914;border:1px solid #0ea5e947}.specialty-onco{color:#a78bfa;background:#8b5cf614;border:1px solid #8b5cf647}:root[data-theme=light] .specialty-onco{color:#6d28d9}.specialty-neuro{color:#f472b6;background:#ec489914;border:1px solid #ec489947}:root[data-theme=light] .specialty-neuro{color:#be185d}.specialty-general{color:var(--color-info);background:#06b6d414;border:1px solid #06b6d447}@keyframes ecgHeartbeat{0%,to{transform:scale(1)}50%{transform:scale(1.02)}}.ecg-heartbeat{animation:4s ease-in-out infinite ecgHeartbeat}.pulse-glow-border{position:relative}.hero-stat-box{background:var(--btn-clinical-bg);border:1px solid var(--border-color);text-align:center;transition:all var(--transition-fast);border-radius:10px;flex-direction:column;gap:3px;padding:12px 14px;display:flex}.hero-stat-box:hover{border-color:var(--border-hover);transform:translateY(-1px)}.hero-stat-number{font-family:var(--font-mono);color:var(--text-main);letter-spacing:-.02em;font-size:1.2rem;font-weight:700}.hero-stat-label{color:var(--text-muted);text-transform:uppercase;letter-spacing:.05em;font-size:.7rem;font-weight:600}.float-card{animation:4s ease-in-out infinite floatCardAnimation}@keyframes floatCardAnimation{0%{transform:translateY(0)}50%{transform:translateY(-6px)}to{transform:translateY(0)}}.rotate-landscape-mode{transform-origin:0 0!important;z-index:99999!important;background:var(--bg-primary)!important;box-sizing:border-box!important;width:100dvh!important;height:100dvw!important;padding:20px 16px!important;position:fixed!important;top:0!important;left:0!important;overflow:hidden auto!important;transform:rotate(90deg)translateY(-100dvw)!important}body:has(.rotate-landscape-mode){overflow:hidden!important}.mobile-rotate-btn{display:none}@media (width<=1024px){@media (orientation:portrait){.mobile-rotate-btn{background:var(--primary);color:#fff;font-family:var(--font-heading);z-index:1000000;cursor:pointer;transition:all var(--transition-fast);border:none;border-radius:99px;justify-content:center;align-items:center;gap:8px;padding:12px 20px;font-size:.85rem;font-weight:700;display:flex;position:fixed;bottom:20px;right:20px;box-shadow:0 4px 16px #0ea5e973}}.mobile-rotate-btn:hover{background:var(--primary-hover);transform:scale(1.05)}.rotated-icon{transition:transform var(--transition-fast);transform:rotate(-90deg)}}@media (width<=1024px) and (orientation:landscape){.app-container{flex-direction:row!important;width:100dvw!important;height:100dvh!important;overflow:hidden!important}.sidebar{border-right:1px solid var(--border-color)!important;border-bottom:none!important;width:250px!important;min-width:250px!important;height:100dvh!important;max-height:none!important}.main-content{box-sizing:border-box!important;width:100%!important;height:100dvh!important;padding:20px 16px!important;overflow:hidden auto!important}.rotate-landscape-mode{box-sizing:border-box!important;width:100%!important;height:auto!important;padding:20px 16px!important;position:static!important;overflow:hidden visible!important;transform:none!important}}